While LSE is a great web server, I think that OLS/nginx with a multi-server control panel like Enhance makes a great combination. With this, you can spin up multiple servers without worrying about licensing fees. For instance, imagine you have 6 or 10 servers and you need to license every one of these. It also doesn't make sense to use LSE when it is geared towards cramming users into a single server while Enhance leans towards separating and managing websites across multiple servers. Isn't this the purpose of a multi-server control panel?
Using Apache is not a choice. Between Nginx and OLS on Enhance, what are you using? Note that Nginx does not yet have mod security, which doesn't make sense if you're using CPguard or any other paid WAF subscription.
Is OLS working good for you ? What are your thoughts ..