From various reports via the support system, the only Enhance related cause we have identified is the failure to install the mta during the 11.0.x update which in turn causes sendmail/postdrop to hang in user accounts and eventually causes excessive memory usage. That's fixed by running on the control panel server:
appcd-cli 1.1.1.1 install-mta
appcd-cli 1.1.1.1 install-imap
Where 1.1.1.1 is the IP of the system with the issue.
Of the other reports we've received, the main user of memory has been mariadb/mysql which wasn't touched by any recent update. In some other cases it was netdata and similar monitoring software which is external to Enhance.